16 results
Duke's Criteria for Infective Endocarditis
Definite IE - Pathologic Criteria:
 • Pathologic lesions - vegetation or intracardiac
for Infective Endocarditis ... demonstrating active endocarditis ... major clinical criteria ... blood cultures ... Immunologic phenomena • Micro
Blood culture contaminants
Grouped by gram negative vs gram positive vs other as well as never/maybe/probably
Some additional
Blood culture contaminants ... Grouped by gram negative ... #Infections #Microbiology ... #Micro #Differential ... #Bloodculture #Bloodcx
Capnocytophaga spp on Culture and Blood Smear
Associated w/ dog/human oral flora, can cause bacteremia in immunocompromised
Capnocytophaga spp ... anaerobe; narrow Gram negative ... #Culture #Blood ... #Smear #clinical ... #microscopy #microbiology
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... culture negative ... infective endocarditis ... #negative #Endocarditis ... InfectiousDiseases #Microbiology
Blood Culture Collection Algorithm - Adult Patients with Suspected Systemic Infection 

Pawlowicz et al evidenced based
Blood Culture Collection ... who meet SIRS criteria ... infections, whose clinical ... tract infection, endocarditis ... #Indications #Criteria
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
infections • Gram-negative ... 13%), Pneumonia, Endocarditis ... microorganism (Culture ... fusiform gram-negative ... #canimorsus #microbiology
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
high index of clinical ... : Serial negative ... blood cultures ... Frequent false-negative ... : + (Negative blood
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... : Blood cultures ... • Coagulase-negative ... • Blood cultures ... -> TEE • Duke Criteria
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
fastidious gram-negative ... to meningitis, endocarditis ... Myocarditis & culture-negative ... is difficult to culture ... #dermatology #clinical
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... negative for 7 ... antimicrobials, clinical ... #Infective #Endocarditis