11 results
Blood culture contaminants
Grouped by gram negative vs gram positive vs other as well as never/maybe/probably
Some additional
Blood culture contaminants ... Grouped by gram negative ... #Infections #Microbiology ... #Micro #Differential ... #Ddx #Diagnosis
Duke's Criteria for Infective Endocarditis
Definite IE - Pathologic Criteria:
 • Pathologic lesions - vegetation or intracardiac
major clinical criteria ... blood cultures ... from 2 separate blood ... Immunologic phenomena • Micro ... #Endocarditis #diagnosis
Capnocytophaga spp on Culture and Blood Smear
Associated w/ dog/human oral flora, can cause bacteremia in immunocompromised
Capnocytophaga spp ... anaerobe; narrow Gram negative ... #Culture #Blood ... #Smear #clinical ... #microscopy #microbiology
How to Determine a Contaminant vs True Infection 

What is the organism? Most 
common contaminants:
• Coagulase-negative ... ) How many blood ... culture sets are ... species from the micro ... #BCx #Laboratory
Diagnosing Brucellosis
Epidemiological Exposures
- Endemic Regions
- Clinical Micro Lab Technicians
- Animal/Vaccine Exposure: Vets, Slaughterhouse workers, hunters
- Unpasteurized
Endemic Regions - Clinical ... Micro Lab Technicians ... cheese, ice cream) Clinical ... : Culture (blood ... #Criteria #Workup
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
spread of the Gram-negative ... Laboratory Diagnosis ... : • 2 sets of blood ... cultures should ... #Management #Microbiology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... : Blood cultures ... • Coagulase-negative ... • Blood cultures ... -> TEE • Duke Criteria
Guide to Interpretation of Positive Blood Cultures

I arrange the potential Gram stain results that one can
Interpretation of Positive Blood ... Remember that clinician ... Interpretation #Laboratory ... #Microbiology # ... Diagnosis
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... : Blood cultures ... Negative: • Bartonella ... : • Blood cultures ... → TEE • Duke Criteria
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Gram stain and culture ... ANAs; thus, a negative ... : • Complete blood ... ANA and RF (if clinical ... #workup #diagnosis