20 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Direct antiglobulin test ... normal • DAT negative ... #Diagnosis #Management ... #Algorithm #hematology
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
and Management ... spread of the Gram-negative ... the preferred test ... typically part of the workup ... • Test all patients
Diarrhea Workup and Management Algorithm in Transplant Patients
First Tier Microbiologic-Testing:
1. C. difficile PCR (Stool)
2. CMV qPCR
Diarrhea Workup ... Breath test for ... above testing negative ... #Transplant #diagnosis ... #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
value is low, tests ... indirect antiglobulin tests ... - Negative, ruling ... WBC count and differential ... #Workup #Hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Effusions: - Hematologic ... #diagnosis #msk ... #physicalexam
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Positive pathergy test ... is a skin prick test ... Behcet disease) Differential ... #diagnosis #management ... signs #symptoms #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
• Some false negative ... specific laboratory tests ... #management #phenotypes ... #workup #treatment ... #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... younger pts) Differential ... test #cold # ... hemolytic #anemia #hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... you’ll do a good workup ... Best to have an ... #workup #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... affected areas and if negative ... blockers had the best ... diagnosis #management ... #Dermatology