81 results
Hemolytic anemia in Wilson's disease

#Wilsons #Disease #hemolytic #anemia #Hematology #pathophysiology
anemia in Wilson's disease ... #Wilsons #Disease ... hemolytic #anemia #Hematology ... #pathophysiology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Anemia (AIHA) Pathophysiology ... C3 positive or negative ... mediated - DAT: IgG negative ... Hemolytic #Anemia #Pathophysiology ... #diagnosis #hematology
Raynaud's Phenomenon on Physical Exam

#Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
Raynauds #Syndrome #disease ... phenomenon #clinical #video ... fingers #hands #rheumatology
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Dupuytren's Contracture (Palmar Fibromatosis) on Physical Exam

#Dupuytrens #Contracture #Palmar #Fibromatosis #clinical #video #physicalexam #msk #hand #orthopedics
Fibromatosis #clinical #video ... #physicalexam #msk ... #orthopedics #rheumatology
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Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Cold Agglutinin Disease ... AIHA (7-8%) DAT-negative ... Diagnosis #Table #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative ... diagnosis #algorithm #rheumatology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
Hemolysis DAT Negative ... Cold agglutinin disease ... Autoimmune #Hemolysis #hematology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... female-predominant disease ... of autoimmune disease ... , First-degree relative ... #hepatology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... - Pathophysiology ... of disease and ... #Pathophysiology ... Complications #Hematology