13 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Comparison: • Primary ... Symptoms: Commonly no signs ... Bone/joint pain Psychiatric ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... Signs/Symptoms: ... Pretibial myxedema #Primary ... Hyperthyroidism #endocrinology ... #pathophysiology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... an absolute or relative ... Insulin is the primary ... #Pathophysiology ... DKA #Diabetes #Endocrinology
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
thought to cause Negative ... Schizophrenia #pathophysiology ... diagnosis #symptoms #signs ... #psychiatry #positive ... #negative
Calcium homeostasis is a process controlled by chiefly by hormones vitamin D and PTH. 
Vitamin D
regulated by classical negative ... It is regulated primarily ... #Pathophysiology ... #Endocrinology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
normal mood - Primary ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
patients with a negative ... hypertension and signs ... renal bruit or signs ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary