12 results
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Tremor Ataxia Ocular ... Bradycardia Pulmonary ... SideEffects #Adverse #Diagnosis ... #Management #Pharmacology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... hepatitis • Pulmonary ... • Ocular: uveitis ... #management #treatment ... #rheumatology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
• Reticular + Nodular ... pneumonitis Diagnosis ... suggestive but not diagnostic ... pulmonary toxicity ... #diagnosis #management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
concentration PET-CT ... Imaging (→ Diagnostic ... • Some false negative ... #management #phenotypes ... workup #treatment #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... emboli, and ocular ... levels >1g/L • Negative ... cryoglobulins • Negative ... #rheumatology #
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... A nonpruritic macular ... dysfunction, and negative ... #rheumatology # ... management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Mediastinal mass) • CT ... lymph node biopsy (diagnostic ... physical exam, CT ... Hodgkins #lymphoma #diagnosis ... #oncology #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... affected areas and if negative ... sites such as the collar ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Pneumonia (CAP) - Diagnosis ... and Management ... radiograph or CT ... screening: High negative ... #Pulmonary #Community
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
host): • Chronic pulmonary ... symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... , ocular, or disseminated ... #Management #Infections