19 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... or AST > ALP): ... Cholestatic Pattern (ALP ... #diagnosis #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis ... discomfort Signs: Jaundice ... Elevated ALP 2. ... #Cirrhosis #Diagnosis ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Diagnosis Algorithm ... • Pregnancy - AFLP ... Duct Stone • Biliary ... Others #LFTs #Hepatology ... #Diagnosis #Algorithm
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Diagnosis Algorithm ... ALP: - Enzymes ... - Increased ALP ... #Diagnosis #Algorithm ... #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... GGT/5-NT: ↑ - ALP ... hepatitis: < 1 • Cirrhosis ... #diagnosis #algorithm ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... hyperpigmentation • Jaundice ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... (DIC, ascites, jaundice ... infiltration) Differential ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
disease • If ALP ... hepatitis: < 1 • Cirrhosis ... liver #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Diagnosis Algorithm ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... Diagnosis #Algorithm ... #Causes #Hepatology