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diagnosis differential nephrology metabolic causes chloride pathophysiology urinary hypochloremia hypokalemia im low mechanismofaction metabolicalkalosis nejm nongap pharmacology potassium primary resistance
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop Diuretic ... Action and Resistance ... lumen by organic anion ... Pathophysiology #Nephro ... #IM #LoopDiuretic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... diuretic use, Bartter ... Differential #Diagnosis #Algorithm
Major Segments of the Nephron and their Functions - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... vasopressin control #Nephron ... #Segments #Function
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... High Urine Cl-: Diuretics
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic Alkalosis ... Differential Diagnosis Algorithm ... Vomiting • NG suction ... fibrosis • Remote diuretic ... #Metabolic #Alkalosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Low Cl intake, Diuretics ... High Urine Cl-: Diuretics
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... diuretic use, Bartter ... Chloride #urine #Algorithm
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... - Metabolic alkalosis ... Ileostomy - NGT suction ... RENAL LOSS: - Diuresis ... cause metabolic alkalosis
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Differential Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... GI losses (NG suction ... • Discontinued diuretic ... Differential #Diagnosis #Algorithm
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm GI Losses - Gastric • Vomiting • NG suction GI
Causes of Metabolic Alkalosis ... Differential Diagnosis Algorithm ... Vomiting • NG suction ... tubular transport • Diuretics ... Differential #Diagnosis #Algorithm
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