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Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... Sites of Action ... critical-care-nephrology#book-info #Nephron ... #Diuretics #Site ... #Nephrology #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... of Action Diuretics ... Adenosine #Nephron ... #Pathophysiology ... #Action #nephrology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Hormones Acting ... on the Nephron - ... Site of Action ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop Diuretic ... Action and Resistance ... lumen by organic anion ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... acid and most diuretics ... vasopressin control #Nephron ... Segments #Function #Pathophysiology ... #Tubules #Table
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
conditions all of which cause ... that has a normal anion ... different types/causes ... Diagnosis #IM #Nephro ... RenalTubularAcidosis #Features #Table
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... dose salicylates, diuretics ... tubule in the nephron ... blood into the nephron ... Hyperuricemia #Pathophysiology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Metabolic Acidosis Causes ... and chronic) Causes ... Generalized distal nephron ... Potassium-sparing diuretics
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... (AKI, Post-AKI diuresis ... ) RAAS Active (or ... differential #diagnosis #table
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... extracellular anion ... Differential #Diagnosis #Algorithm ... #Pathophysiology