8 results
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... dose salicylates, diuretics ... Release of purine bases ... Hyperuricemia #Pathophysiology ... #Complications
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... reabsorption in the nephron ... kidney), which causes ... are similar to diuretics ... have good kidney function
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... lost via osmotic diuresis ... has good renal function ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... transport, renal function ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... metabolic acidosis: Diabetic ... #causes #urinary
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... essential for cell function ... Glycosylation - AGE cause ... #DiabeticFoot #pathophysiology ... #complications
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... pressure: Active diuretic ... metabolic acidosis • Diabetic ... the indicated causes