14 results
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
a Mechanism of Diuretic ... doses of loop diuretics ... thiazide-sensitive sodium chloride ... channel, and the chloride–bicarbonate ... #Pathophysiology
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
compete with chloride ... sodium–potassium–chloride ... (NKCC2), which is ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Differential Diagnosis Algorithm ... Vomiting • NG suction ... fibrosis • Remote diuretic ... resistant: • Current diuretic ... Differential #Diagnosis #Algorithm
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... RENAL LOSS: - Diuresis ... • Fatigue Chloride ... #Pathophysiology ... #Nephrology #Chloride
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... pressure: Active diuretic ... Differential #Diagnosis #Algorithm
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... loop or thiazide diuretics ... pressure: Active diuretic ... Urine chloride is ... #urine #Algorithm
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... #Segments #Function ... #Pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... Gitelman Syndrome is ... thiazide-sensitive sodium-chloride ... delivery to distal nephron ... Gitelman #Syndrome #Pathophysiology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
reabsorption in the nephron ... are similar to diuretics ... have good kidney function ... Each is available
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
Bowel Syndrome (IBS ... ) - Pathophysiology ... and Management Algorithm ... Younger age, Other functional ... Pregabalin #IBS