11 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Proximal tubule Bartter ... loop of Henle Gitelman ... #Nephron #Defects ... #Pathophysiology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... Diagnosis Algorithm ... tubular acidosis • Gitelman's ... syndrome • Bartter's ... #Causes #Classification
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Extra-renal Losses ... thiazide diuretics, Bartter ... syndrome, Gitelman
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Hypokalemia - Differential ... Diagnosis Algorithm ... hypokalemia • Renal ... • Diuretics, Bartter's ... syndrome, Gitelman's
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Hypokalemia (renal ... ratio 0.5%) Differential ... Sjögren syndrome, Renal ... syndrome • Pseudo Bartter-Gitelman ... nephrology #management #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... suggests extra-renal ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... #differential #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... Distribution - better ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm