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diagnosis differential nephrology causes hypokalemia alkalosis metabolic potassium syndrome chloride defects disorders fanconi hematology hypochloremia liddle localization lymphomas lymphoproliferative management
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Localization of Renal ... Proximal tubule Bartter ... loop of Henle Gitelman ... #Nephron #Defects ... #Pathophysiology
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Low intake ... oral intake Renal ... tubular acidosis • Gitelman's ... syndrome • Bartter's ... #Causes #Classification
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Extra-renal Losses ... loss (Diarrhea) Renal ... thiazide diuretics, Bartter ... syndrome, Gitelman
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Differential #Diagnosis #Algorithm
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Differential #Diagnosis #Algorithm
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Decreased Intake: • Low ... - Diarrhea • RENAL ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... suggests extra-renal ... consumption • Low ... Emesis, Diuretics, Bartter ... syndrome, Gitelman
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal or low ... • Hypokalemia (renal ... Sjögren syndrome, Renal ... syndrome • Pseudo Bartter-Gitelman ... nephrology #management #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Distribution - better ... B-Cell ~90% • Low ... Lymphoproliferative #Disorders #Classification ... #pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... Differential #Diagnosis #Algorithm
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