36 results
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
require empiric acyclovir ... The risk of acyclovir-induced ... nephrotoxicity ... favor the use of acyclovir ... -Acyclovir is nephrotoxic
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Acyclovir - Pharmacology ... Toxicity: AKI, Neurotoxicity ... TheIDtrivia #Acyclovir
Drug-induced renal disorders - The most commonly used nephrotoxic drugs

#Pharmacology #Nephrotoxicity #Drugs #Medications #Most #Common #DrugInduced
#Pharmacology #Nephrotoxicity
Urine Microscopy - Kidney Stones and Crystals 

Uric Acid, Cystine, Hippurate, Cloth Fiber, Tyrosine, CaOx, CaP,
CaCO3, Struvite, Acyclovir
Varicella (Chickenpox) - Crops of vesicles in various stages of healing 

Treatment 
• Healthy g 12
Immunocompromised or > 12: Acyclovir
TB Man - Mnemonic for Anti-Tuberculosis Medication Toxicities
Isoniazid - peripheral neuropathy, neurotoxicity, hepatotoxicity
Streptomycin - ototoxicity
Ethambutol -
peripheral neuropathy, neurotoxicity
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
β-lactam agents, Aciclovir
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Hearing Loss Neurotoxicity ... Hypotension Nephrotoxicity
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Methotrexate, Orlistat, Acyclovir
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Crystal nephropathy: Acyclovir