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management differential signs hematology lupus sle systemic vasculitis activation aion algorithm ana anteriorischemicopticneuropathy antibodies antinuclear behcet classification cryofibrinogenemia dermatologic dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , macular, patchy ... Diffuse alveolar hemorrhage ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
disorder of the optic nerve ... with splinter hemorrhages ... Clinical manifestations ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... Systemic lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... dysfunction • Hemorrhagic ... #Diagnosis #Management ... #Hematology #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... rash (6.7%) • Hemorrhagic ... Differential Diagnosis ... • Goodpasture syndrome ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... ischemia • Skin: Erythematous ... muscle weakness • Nerves ... • Progressive symptoms ... #Rheumatology
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