14 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... water Extrarenal hypotonic ... perspiration Renal ... insipidus • Nephrogenic ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... of hypotonic hyponatremia ... volume-based algorithm ... +K / serum Na >1 ... Hypothyroidism, Adrenal
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... NORMAL PLASMA OSMOLALITY ... hypothyroidism • adrenal ... Diagnosis #Workup #Algorithm
Causes of Polyuria - Differential Diagnosis Algorithm
Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min)
Osmotic
Causes of Polyuria ... Differential Diagnosis Algorithm ... Recovery from Acute Renal ... Kidney • Nephrogenic ... #Causes
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... 1) Check Urine ... insipidus (central or nephrogenic ... Diagnosis #Workup #Algorithm ... #nephrology #sodium
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Algorithm Isotonic ... , Recent TURP Hypotonic ... Syndrome, Chronic Renal ... #diagnosis #causes ... #nephrology #sodium
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Weakness, fatigue, nausea ... , hypotension, hyponatremia ... ACTH) stimulation test ... insufficiency • Low or normal
Hyponatremia - Diagnostic Evaluation Algorithm

Step 1: Consider whether Posm may actually be normal or elevated
Step 2:
Evaluation Algorithm ... Step 1: Consider ... may actually be normal ... Consider additional tests ... considered likely, the cause
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... SIADH — look for cause ... hourly • Identify Cause ... #Management #algorithm ... #treatment #sodium
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Clarity Dipstick test ... specific gravity test ... not be used with normal ... renal function. ... (AKI) FE Na < 1%