18 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... administration Step 3. ... • nephrotic syndrome ... Workup #Algorithm #Nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm 1) ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) Sodium ... from tubules 3) ... #hyponatremia # ... comparison
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
output is a clue). 1) ... post-obstructive 3) ... Diabetes Insipidus: neurogenic ... ([Na] / 140) - 1) ... #sodium
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... 2 cases/100,000 ... Decreased / Absent Reflexes ... /constipation, hyponatremia ... management #treatment #neurology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
1) Is it hypotonic ... the underlying cause ... demyelination syndrome ... Treatment #management #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... +K / serum Na >1 ... : SIADH, Renal Sodium ... Cirrhosis, Nephrotic syndrome ... #nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... to 2 cases per 100,000 ... depressed deep tendon reflexes ... 3 to 1/2 of patients ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
• Prevalence: 1: ... - Emergency Causes ... cord • Guillain-Barre ... differential #diagnosis #causes ... #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
should be done): 1. ... heart failure, neurologic ... • Other: 1. ... Neurologic disorders ... , and Guillain-Barre