11 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
water retention 1) ... Serum Osmolarity 2) ... Urine Osmolarity 3) ... Low Uric Acid → SIADH ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... Step 2. ... administration Step 3. ... EUVOLEMIC • SIADH
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) ... Sodium loss from ... tubules 3) Naturiesis ... #hyponatremia #
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Workup Step #1 ... history Step #2 ... Uglucose Step #3 ... #Management #Algorithm ... #Sodium #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... 1) Check Urine ... renal mechanism 2) ... insipidus (central or nephrogenic ... #nephrology #sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... post-obstructive 3) ... Diabetes Insipidus: neurogenic ... Diagnosis #Treatment #management ... #nephrology #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... Basically anything 2. ... hospitalization) 3. ... promoting passive sodium ... #Management #hyponatremia
DDAVP Clamp Protocol in Hyponatremia
 • Stop any maintenance fluids.
 • Start DDAVP 2 mcg IV
DDAVP Clamp Protocol ... in Hyponatremia ... • Start DDAVP 2 ... NaCl (1-1.5 ml/ ... #management #nephrology
Hyponatremia Diagnostic Algorithm
1) Check serum osmolality
2) Check urine osmolality
3) ADH Dependent - Check volume status, urine
Algorithm 1) Check ... serum osmolality 2) ... urine osmolality 3) ... status, urine sodium ... #nephrology
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Then, ask 3 questions ... 1) Is it hypotonic ... 2) Is ADH elevated ... Diagnosis #Treatment #management ... #nephrology #sodium