25 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Workup Step 1 ... Repeat the sodium ... EUVOLEMIC • SIADH ... hypothyroidism • adrenal ... Workup #Algorithm #Nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Low Uric Acid → SIADH ... High Uric Acid → renal ... Diagnosis #Algorithm #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... perspiration Renal ... insipidus • Nephrogenic ... Differential #Diagnosis #Causes ... #nephrology #sodium
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... treat underlying cause ... Pulmonary Diseases ... , SSRIs) - SIADH ... #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... +K / serum Na >1 ... restriction alone in SIADH ... , Renal Sodium loss ... #nephrology
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... congenital disorders Nephrogenic ... diseases (e.g. ... Diagnosis #Table #Causes
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Workup Algorithm 1) ... , Ingestion Renal ... insipidus (central or nephrogenic ... Workup #Algorithm #nephrology ... #sodium
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... restriction: • Restrict 1 ... promoting passive sodium ... #Management #hyponatremia ... #nephrology #treatment
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
disease, water ... Diabetes Insipidus: neurogenic ... ([Na] / 140) - 1) ... Diagnosis #Treatment #management ... #nephrology #sodium
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... purposes, restrict to 1 ... promoting passive sodium ... #Management #hyponatremia ... #nephrology #treatment