12 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... renal mechanism 2) ... #Workup #Algorithm ... #nephrology #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... Step 2. ... #Diagnosis #Workup ... #Algorithm #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... nephrotic syndrome • Hyponatremia ... and euvolemic hyponatremia ... #Nephrology #Pharmacology ... #Medications #Table
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... renal perfusion (Heart ... #differential #diagnosis ... #table #sodium ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... cell epithelial sodium ... of epithelial sodium ... #Nephrology #Diagnosis ... #Differential #Table
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
depletion - Heart ... e.g. pneumonia, COPD ... exacerbation) - Drugs ... #Table #Causes ... #Sodium
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
water unavailable 2) ... Osmotic Diuresis ... Diabetes Insipidus: neurogenic ... Treatment #management #nephrology ... #sodium
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
tissue perfusion 2. ... infection • Neurogenic ... decompensated heart ... due to loss of sodium ... warm #wet #dry #table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Toxins - Drugs ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... Loop diuretics for ... causes #treatment #nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... illness → Hypernatremia ... involvement: Muscles, Kidneys ... encephalopathy) 2.