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diagnosis differential nephrology causes classification high hyponatremia lactate lactic management psychiatry acquired adh algorithm anticonvulsants bonestrength bulimianervosa cancer cardiology complications
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Epithelial #Inherited #Defects
Causes of Hypernatremia - Differential Diagnosis Inadequate water intake: • Lack of access to water Extrarenal hypotonic fluid
Causes of Hypernatremia ... concentrating defect ... insipidus • Nephrogenic ... administration #Hypernatremia ... Causes #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Distal Renal Tubular Acidosis Distal RTA is the true Nephrogenic RTA and can be truly divided into
Renal Tubular Acidosis ... RTA is the true Nephrogenic ... • H secretion defect ... diseases(Sjogren's Syndrome ... Renal #Tubular #Acidosis
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... Collapse: • Pathophysiology ... consciousness, Coma/seizure
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... and Treatment Hyponatremia ... demyelination syndrome ... of symptomatic (seizures ... management #nephrology #sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... True hyponatremia ... the hypothalamus detect ... #hyponatremia #ADH
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... -> Withdrawal seizure ... vomiting, diarrhea, hyponatremia ... #SideEffects #Pathophysiology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Hyperviscosity Syndrome ... • Neurologic deficits ... • Early death Neutropenic ... : Tumor Lysis Syndrome ... coma SIADH: • Hyponatremia
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