8 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... cell epithelial sodium ... of epithelial sodium ... acidosis - alpha-Intercalated ... #Nephrology #Diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
, Gitelman syndrome ... tubular acidosis ... tubular acidosis ... the excretion of sodium ... urine #Algorithm #nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
Acute Kidney Injury ... disease - Acute tubular ... causes: sepsis, meds ... obstruction) • Neurogenic ... Classification #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia ... • Nephrogenic ... and euvolemic hyponatremia ... Excretion #Diuresis #Nephrology ... #Medications #Table
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... involvement: Muscles, Kidneys ... consciousness, Coma/seizure
Metabolic Causes of Kidney Stones in Children
 • Calcium Oxalate: Primary Hyperoxaluria type 1-3, Secondary Hyperoxaluria
Metabolic Causes of Kidney ... : Distal Renal Tubular ... Acidosis (RTA), ... #Stones #pediatrics ... #nephrology #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... nephrotoxicity to kidney ... tubular cells ... causes #treatment #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... , Renal tubular ... acidosis (RTA)) ... tachycardia • Seizures ... #diagnosis #nephrology