19 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Epithelial #Inherited #Defects
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... concentrating defect ... insipidus • Nephrogenic ... administration #Hypernatremia ... Causes #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Distal Renal Tubular Acidosis
Distal RTA is the true Nephrogenic RTA and can be truly divided into
Renal Tubular Acidosis ... RTA is the true Nephrogenic ... • H secretion defect ... diseases(Sjogren's Syndrome ... Renal #Tubular #Acidosis
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Hypernatremia - ... Hypernatremia ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... management #nephrology #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
and Treatment ... Treatment: Treatment ... demyelination syndrome ... of symptomatic (seizures ... management #nephrology #sodium
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... - Metabolic acidosis ... consciousness, Coma/seizure
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
Hyponatremia (<135 ... asymptomatic to seizures ... True hyponatremia ... the hypothalamus detect ... #hyponatremia #ADH
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
before beginning treatment ... Heavy exercise - Seizures ... - Compartment syndrome ... B3: Hereditary Defects ... myopathies - Defects