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diagnosis nephrology causes hyponatremia management treatment algorithm defects ebv epithelial gitelman heat heatstroke hypokalemia hypotonic hypovolemia illness inherited kidney osmolality
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... - Differential ... Insensible losses Sodium ... Insipidus (Decr ADH ... Diagnosis #Table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #differential # ... diagnosis #table
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... #Differential # ... Algorithm #nephrology #sodium
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... - Cirrhosis Syndrome ... Inappropriate ADH ... Diagnosis #Table ... #Causes #Sodium
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
cell epithelial sodium ... of epithelial sodium ... renal tubular acidosis ... Nephrology #Diagnosis #Differential ... #Table
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
osmolality helps to differentiate ... asymptomatic to seizures ... stimulated in states of low ... activated in states of low ... #hyponatremia #ADH
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 2) Is ADH elevated ... demyelination syndrome ... of symptomatic (seizures ... management #nephrology #sodium
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... exertion/training - Seizures ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia ... per day until stable
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... ratio 0.5%) Differential ... Renal tubular acidosis ... tachycardia • Seizures
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