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diagnosis differential nephrology causes hyponatremia management defects ebv epithelial gitelman hypokalemia hypotonic hypovolemia kidney osmolality pathophysiology physiologic potomania raas rhabdomyolysis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... cell epithelial sodium ... of epithelial sodium ... acidosis - alpha-Intercalated ... #Differential #Table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
Etiologies of Hypernatremia ... Insensible losses Sodium ... Insipidus (Decr ADH ... Insipidus (Incr ADH ... Differential #Diagnosis #Table
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... - Cirrhosis Syndrome ... Inappropriate ADH ... Differential #Diagnosis #Table ... #Causes #Sodium
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
asymptomatic to seizures ... stimulated in states of low ... activated in states of low ... in the renal tubules ... #hyponatremia #ADH
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
• Inherited (AR) ... thiazide-sensitive sodium ... alkalosis • Normal or low ... acidosis (RTA)) ... tachycardia • Seizures
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
exertion/training - Seizures ... Aldolase ↑ • LDH ... Hyperuricemia • Hyponatremia ... formation: Renal tubular ... per day until stable
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