9 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... mechanism 2) Volume Status ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
According to Volume Status ... - Cushing's syndrome ... Gestational DI, Nephrogenic ... , Loop diuretics ... Comparison #Table #Nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
and Workup Step ... Repeat the sodium ... Assess volume status ... volume loss - diuretics ... • nephrotic syndrome
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
, Dehydration: neurologic ... unavailable 2) Osmotic Diuresis ... Diabetes Insipidus: neurogenic ... , nephrogenic 4 ... #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... Assess volume status ... demyelination syndrome ... of symptomatic (seizures ... #sodium
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Hyponatremia ... • Nephrogenic ... Tolvaptan) • Treatment ... and euvolemic hyponatremia ... #Nephrology #Pharmacology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
exertion/training - Seizures ... Toxins - Drugs - Statins ... Hyperuricemia • Hyponatremia ... Loop diuretics for ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... with thiazide diuretic ... tachycardia • Seizures ... Rhabdomyolysis Treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Emergencies Neutropenic ... full infectious work-up ... days → add fungal work-up ... Adjuncts: loop diuretics ... consciousness, seizures