23 results
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
lymphadenopathy Early Latent ... Latent - > 1 year ... Asymptomatic Early Neurosyphilis ... → Late Neurosyphilis ... #timeline #progression
Neurosyphilis - Progression Timeline
Early vs Late

Dr. Valeria Roldán @valeroldan23

#Neurosyphilis #Progression #Timeline #diagnosis #neurology
Neurosyphilis - ... Progression Timeline ... Early vs Late ... valeroldan23 #Neurosyphilis ... #Progression #Timeline
Syphilis - CDC 2021 Treatment Guidelines
Recommended Regimen:
 • Primary, secondary, and early latent: adults (including pregnant
Syphilis - CDC 2021 ... Treatment Guidelines ... intervals • Neurosyphilis ... #Neurosyphilis ... #CDC #CDC2021 #Treatment
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... Symptomatic early neurosyphilis ... Syphilis - Latent ... Syphilis - Late ... Neurosyphilis.
Treatment of Syphilis
Early:
 • Penicillin G, 2.4 million units IM once OR
 • Doxycycline 100mg BID
Treatment of Syphilis ... BID for 2 weeks Late ... BID for 4 weeks Neurosyphilis ... BostonChiefs #Syphilis ... #Treatment #management
Syphilis - Diagnosis and Management - Primary vs Secondary vs Tertiary
Primary Syphilis
 • Localized lymphadenopathy
 •
Syphilis - Diagnosis ... Tertiary Primary Syphilis ... Chancres Secondary Syphilis ... • Neurosyphilis ... Secondary #Tertiary #Comparison
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Manifestations and Treatment ... the absence of treatment ... Syphilis: • Patient ... after infection Treatment ... (no neuro) • Neurosyphilis
Treatment Recommendations for Syphilis in Non-Pregnant Adults by Syphilis Stage

Incubating Infection, Primary, Secondary, Early Latent Syphilis:
Treatment Recommendations ... Secondary, Early Latent ... Latent or Latent ... daily for 28 days Neurosyphilis ... #Treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... progress to the latent ... and late stages ... loss (10-15%) ▪ Neurosyphilis
Neurosyphilis - Treponema pallidum - Diagnosis Algorithm
Lumbar Puncture Indications:
 • Neuro / Ocular symptoms
 • HIV
Neurosyphilis - ... CD4 count) • Treatment ... Failure • Tertiary Syphilis ... Elevated Protein Treatment ... NUIM_Chiefs #Neurosyphilis