11 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... tests in pregnancy ... #obgyn #obstetrics ... #hepatology #diagnosis ... #differential #
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... exchange 2) Fatty liver ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology ... #obstetrics #obgyn
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
of Pregnancy (AFLP ... #hepatology #obstetrics ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... AIH, Wilsons, Pregnancy ... #hepatology #LiverFunctionTests
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Highest • Bone • Liver ... - Drugs - Pregnancy ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... RBC (hemolysis, bleeding ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... RBC (hemolysis, bleeding ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis