11 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Elevated Liver tests ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Elevated Liver tests ... Bloodman #Pregnancy #Thrombocytopenia ... #AFLP #obstetrics ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... K), H. pylori test ... #Causes #Workup ... #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
- Differential Diagnosis ... purpura (TTP) • HELLP ... von Willebrand's disease ... Algorithm #Causes #Obstetrics ... #OBGyn
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... of underlying disease ... 3) Optional tests ... #workup #Differential ... #Diagnosis #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... #Algorithm #workup ... #hematology #testing
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... ) Differential Diagnosis ... Preeclampsia, HELLP ... #obstetrics #obgyn ... #diagnosis #management
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... , no necrosis HELLP ... features: Hemolysis, Thrombocytopenia ... #obstetrics #hepatitis ... #differential #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... hallmark for the disease ... value is low, tests ... indirect antiglobulin tests ... #Workup #Hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... Best to have an ... expert around to help ... #Algorithm #workup ... #hematology