10 results
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) ... anemia (MAHA) Pathophysiology ... Biopsy to confirm diagnosis ... #Crisis #rheumatology ... #nephrology #diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... Diagnosis Approach ... with previously stable ... heart failure, neurologic ... Neurologic disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... l MD SOAP) - Risks ... (CVID, WAS), (neurologic ... #Workup #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
• Hypertensive crisis ... may precede the neurologic ... Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... Reversible course Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... initiation • Differential ... Anaphylaxis, Acute Renal ... #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes • Iritis ... syndrome - SLE Neurologic ... Heberden's nodes ... #joint #pain #differential ... #diagnosis #rheumatology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Mutism Pathophysiology ... #PhysicalExam #neurology ... #comatose #diagnosis
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
infection that cross-reacts ... dissociation - Of note ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... #management #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... pulmonary and renal ... affects the skin, neurologic ... Mucocutaneous lymph node ... #Diagnosis #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... , and possibly renal ... (e.g. incidental ... peripheral lymph nodes