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diagnosis antidrugantibodies antitnffailure checkpointinhibitor differential druglevels gibleed immune lower resistance upper
Upper and Lower Causes of GI Bleed Upper: • Esophagus: Tear (Mallory Weiss, Boerhaave syndrome), Variceal, Esophagitis,
Upper and Lower Causes ... of GI Bleed Upper ... , UC/Chrons (IBD ... Radiation CMC IM ... #algorithm
Algorithm for managing the failure of anti-TNF therapy. ADA=anti-drug antibody; IM=immunomodulator; MOA=mechanism of action; TNF=tumor necrosis
Algorithm for managing ... anti-drug antibody; IM ... necrosis factor #Management ... #GI #IM #IBD #AntiTNFFailure ... #BMJ
Immune Checkpoint Inhibitor-Mediated Colitis Grade of Disease Severity: • G1: Increase < 4 BMs/day over baseline; mild
Inhibitor-Mediated Colitis ... -4 • Consult GI ... CheckpointInhibitor #Colitis ... #diagnosis #management ... #algorithm #IBD
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