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diagnosis management signs differential clinical algorithm pathophysiology treatment cardiology pediatrics peds causes neurology syndrome comparison physicalexam table video msk hematology
Causes of Urticaria Immunoglobulin E (IgE) mediated - Aeroallergens - Contact allergen - Food allergens - Insect
Immunoglobulin E (IgE ... infections Non-IgE ... Differential #Urticaria #IgE ... #Mediated #NonIgE
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 Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Mechanisms Type I - lgE ... Allergen-specific lgE ... cross-linking of lgE ... antigen - IgG ... or IgM antibody
Eosinophilic Esophagitis (EoE) - Spectrum of Response Non-response: • Histology: Persistent eosinophilia, ≥ 15 eos/hpf • Symptoms:
15 eos/hpf • Symptoms ... : Persistent symptoms ... decrease in a symptom ... : Decreased symptoms ... : Symptom resolution
IgM and Non-IgM - Risk and Type of Progression #EBM #Honc #MGUS #Progression #IgM #NonIgM #MultipleMyeloma
IgM and Non-IgM ... #Progression #IgM ... #NonIgM #MultipleMyeloma
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
IgM MGUS: • Serum ... IgM monoclonal ... constitutional symptoms ... or IgG isotype ... (rarely IgD or IgE
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Mediator: lgE ... Immunological Mediator: IgM ... + IgG • Immunological ... Immunological Mediator: IgG ... Contact Dermatitis (ie
Types of hypersensitivity reactions Type I - lgE-Mediated, Within I Hour (Anaphylaxis) Type II - IgG or IgM
reactions Type I - lgE-Mediated ... Anaphylaxis) Type II - IgG ... or IgM Cytotoxic
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
abnormalities (i.e ... expression - Age ... old; F>M Signs/Symptoms ... Diagnosis #Signs #Symptoms
Allergic Bronchopulmonary Aspergillosis (ABPA) WHAT IS IT? Hypersensitivity response to Aspergillus fumigatus in the airways • Primarily affects
ARE THE CLINICAL SYMPTOMS ... Elevated Total IgE ... Aspergillus specific lgE ... and Aspergillus IgG ... voriconazole) • Anti-lgE
Chest Pain Differential By Symptom Characteristics - Dr. Andrew Perry https://twitter.com/Perrycardium #ChestPain #Differential #Symptoms #Characteristics #Diagnosis
Differential By Symptom ... #Differential #Symptoms
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