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diagnosis oncology mds myelodysplastic anemia aplastic cardiology chf clinical criticalcare differential differentiation essential et foamed heartfailure icu leukostasis lysis myelodysplasia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... limb ischemia, bowel ... values: WBC >100k ... TLS #diagnosis #management ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... old, ~10,000 new cases ... cell transplant is ... #treatment #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Diagnosis: • Labs ... 500 mg QD until normal ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... • Treatment is ... • Treatment algorithms ... concentration in the normal ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... aplastic anemia) Labs ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... factor (GCSF) treatments ... blood cells appear normal ... #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
are usually near-normal ... • Treatment is ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
lab markers such ... acute coronary syndrome ... cause and perhaps ... #differential #algorithm ... #management #cardiology
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