14 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
some patients) Normal ... disease, Acute ... : Alcohol use, Liver ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... viral hepatitis: ... #injury #hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... viral hepatitis: ... • Gilbert's syndrome ... #differential #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
disease, Hepatic ... dechallenge • Acute ... hepatitis fibrosis ... • Autoimmune hepatitis ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... Clues to non-cirrhotic ... • Cirrhosis/acute ... hepatitis • Infiltrative ... Diagnosis #causes #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... to acute liver ... Other Etiology of Hepatitis ... #Autoimmune #Hepatitis ... Diagnosis #Management #Hepatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Noninfectious hepatitis ... Cytopenias • Cardiac valve ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... Erythematosus #Diagnosis #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
: - Hepatitis ... (MDS) (normal or ... ) Labs: • Peripheral ... Treatment: ... #oncology #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... and hepatitis ... autoimmune hemolytic anemia ... levels are within normal ... hypogammaglobulinemia #immunology #hematology