39 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Wilsons, Pregnancy - AFLP ... #hepatology #LiverFunctionTests
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Disease #Pregnancy #hepatology ... obstetrics #hepatitis #comparison ... #differential # ... diagnosis #icp # ... HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Antithrombin Ill • Ultrasound ... infiltration) Differential ... Diagnosis: Viral ... Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... • Near normal ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Pregnancy - AFLP ... disease US — Normal ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Infiltrative Labs ... - elevation Labs ... #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... , Metastasis #Liver ... POCUS #radiology #differential ... #diagnosis #comparison ... table #appearance #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... Values and Interpretation ... prothrombin time across labs ... Interpretation #diagnosis ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Calculate R-Value ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #hepatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... ±AKI Initial labs ... hemosiderin • PT/aPTT normal ... #Diagnosis #Management ... #Algorithm #hematology