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diagnosis oncology management lupus sle classification lymphoma systemic autoantibodies chronic cll differentiation druginduced leukemia lymphocytic mds mimickers myelodysplasia myelodysplastic nonhodgkins
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Lymphoma - Comparison ... disease: B symptoms ... • Other hematologic ... #NonHodgkins #comparison ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Cytopenias • Cardiac valve ... Induced Lupus: • Symptoms ... cyclophosphamide) • Hodgkin ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ... ) 30-45% Differential ... autoantibodies #signs #symptoms ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... products that define normal ... number of sites of disease ... Lymphoma Treatment ... classification #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Diagnosis: • Labs ... Diagnosis: >3 symptoms ... initiation • Differential ... 500 mg QD until normal ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... cells can indicate disease ... CLL Labs: 1. ... microglobulin Treatment ... workup #oncology #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Systemic Lupus Erythematosus ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Recurrent oral ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... retinopathy Lab ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... factor (GCSF) treatments ... blood count with differential ... Syndromes #diagnosis #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
systemic lupus erythematosus ... and the systemic symptoms ... plasma cells Labs ... phosphatase - Normal ... diagnosis #management #rheumatology
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