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oncology management lupus sle classification lymphoma systemic autoantibodies chronic cll differentiation druginduced leukemia lymphocytic mds mimickers myelodysplasia myelodysplastic nonhodgkins signs
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Lymphoma - Comparison ... also arise in normal ... disease: B symptoms ... Diagnosis of B-Symptoms ... hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Cytopenias • Cardiac valve ... Induced Lupus: • Symptoms ... , Serositis Labs ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Nephropathy 16% - Oral ... ) 30-45% Differential ... #signs #symptoms ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... products that define normal ... number of sites of disease ... Lymphoma Treatment ... classification #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
: • Labs: leukocytosis ... : >3 symptoms, or ... initiation • Differential ... 500 mg QD until normal ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... cells can indicate disease ... CLL Labs: 1. ... microglobulin Treatment ... workup #oncology #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Systemic Lupus Erythematosus ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Recurrent oral ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... retinopathy Lab ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
systemic lupus erythematosus ... and the systemic symptoms ... plasma cells Labs ... phosphatase - Normal ... #management #rheumatology
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