8 results
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
onset of tender erythematous ... inflammatory disease ... values at presentation ... Criteria #Diagnosis #Hematology ... #Dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... Chronic B-cell activation ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus ... lupus erythematosus ... • HLH Labs: ... #Management #Hematology ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema • NXG • Neutrophilic ... Cryoglobulinemic, Hypo/normo-complementemic ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
febrile neutrophilic ... Diagnosis: • Labs ... initiation • Differential ... 500 mg QD until normal ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... - Recurrent oral ... lupus erythematosus ... retinopathy Lab ... #diagnosis #rheumatology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Summarized Erythema ab ... presenting with erythematous ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... plasma cells Labs ... phosphatase - Normal ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology