15 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
CLL Labs: 1. ... microglobulin Treatment ... • Richter’s Syndrome ... ’s lymphoma or acute ... leukemia • Sezary syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... transformation to acute ... Allogeneic stem cell ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... • Induce blast cell ... Diagnosis: • Labs ... 500 mg QD until normal
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Classification: • Acute ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... Cytopenias • Cardiac valve
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- Summary Acute ... Slightly greater in males ... complete paralysis of all ... CSF PROTEIN - NORMAL ... variants: (1) acute
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Syndrome Acute ... - Most common: Oral ... manifestations Labs ... : • CD4+ T-cell ... antibody test) Treatment
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... importantly, bedside ultrasound ... is vital while lab ... coronary syndrome ... icu #clinical #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... : • Severe oral ... #Rheumatology #
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... protein with a normal ... - Of note, normal ... and cauda equina TREATMENT