8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: • Labs ... Renal Failure Treatment ... 500 mg QD until normal ... #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
include Crackles/Rales ... importantly, bedside ultrasound ... is vital while lab ... heartfailure #chf #criticalcare ... icu #clinical #pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... megakaryocytes and a normal ... aplastic anemia) Labs ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
crusade against “Ab ... ”Normal Saline continues ... #foamed #criticalcare ... management #diagnosis #treatment ... #pharmacology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
anticoagulant treatment ... Idarucizumab - Humanized Fab ... Reversal #NOAC #Oral ... anticoagulant #hematology ... #management #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... : • Severe oral ... Sjogrens #Syndrome #Rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... Histoplasmosis Treatment ... Diagnosis: • Labs ... and Ohio River valleys ... level • A low or normal
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
-70 y/o • 2/3 Males ... mainly in the oral ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology