28 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
or priapism • Lab ... values: WBC >100k ... , + lab signs of ... values: Elevated ... diagnosis #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Diagnosis: • Labs ... Renal Failure Treatment ... 500 mg QD until normal ... #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral ... direct-acting oral ... Anticoagulation #Management #Hematology ... #Oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... (A) Suggested treatment ... DOAC, direct oral ... Anticoagulation #Management #Hematology ... #Oncology
Medical Treatment Algorithm for Chronic Obstructive Pulmonary Disease
Initial medical treatment of chronic obstructive pulmonary disease (COPD)
Medical Treatment ... outpatient setting with oral ... corticosteroid; LABA ... Management #Pulmonary #LABA ... SABA #SAMA #ICS #Pharmacology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Non-autoimmune rheumatologic ... Cytopenias • Cardiac valve ... flares • CRP normal ... Erythematosus #Diagnosis #Rheumatology
LABA/ICS Combination Inhalers
Long-Acting Beta2 Agonists (LABA) + Inhaled Corticosteroid (ICS) - Commonly used in Asthma 
Advair
LABA/ICS Combination ... Beta2 Agonists (LABA ... posts for the COPD treatment ... Listed are the normal ... Naming #Names #Pharmacology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... megakaryocytes and a normal ... aplastic anemia) Labs ... aplastic anemia Treatment ... Aplastic #Anemia #oncology