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diagnosis management rheumatology adrenal druginduced sle acth antiphospholipid apls chronic comparison diarrhea differential dil erythematosus hematology hypercoagulable laboratory stimulation summary
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
- CRP: Usually normal ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... management of SLE • Evolution
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Adrenal Insufficiency ... - Evaluation of ... unclear (often the case ... this indicates normal ... Stimulation #Test #Endocrinology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... - CRP: Usually normal ... • Immunologic Workup
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the ... Evaluation of Chronic ... Causes of acute ... syndromes, Pancreatic insufficiency ... #workup #diagnosis
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
aldosterone - Low in cases ... aldosterone - Often normal ... #Evaluation #laboratory ... diagnosis #testing #endocrinology ... #workup
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... cutaneous-DIL • Evolution ... rheumatology #diagnosis #treatment
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... Algorithm INDICATIONS ... , or placental insufficiency ... maternal chromosomal causes ... excluded Testing: • Lupus
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