23 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... Post-partum • Acute DIC ... - Septic shock, ... Summary #table #comparison ... #diagnosis #hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... DIC • Aminotransferases ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... treatment #management #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Decreased Support Of Dermal ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Differential Diaqnoses ... MAS, Visceral, DIC ... CK, normal biopsy ... splenomegaly • Hepatic
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... intravascularcoagulation (DIC ... amyloidosis #Abnormal ... #differential #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... also arise in normal ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology
Cellulitis: Acute inflammation is clearly seen in the image on the left. The picture on the
right is of a normal ... foot for comparison ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... Acquired: • Heparin ... Warfarin • Acute DIC ... disease • Acute DIC ... #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management