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differential management sle algorithm druginduced erythematosus summary systemic antiphospholipid apls associations bleeding bruising causes coagulation connectivetissuediseases ctild defects deficiencies dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... - CRP: Usually normal ... • Immunologic Workup ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Hemophilia A - Deficiency ... Hemophilia B - Deficiency ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SLE : systemic lupus ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Elevated ESR, Normal ... muscle weakness • Normal ... uncommon 5-15% of lupus ... #differential #diagnosis ... #comparison #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor and lupus ... Willebrand syndrome • Lupus ... #Differential #Diagnosis ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... disease • Prolidase deficiency ... Erythematosus #Diagnosis ... #Rheumatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Normal ... a storage pool deficiency ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Clotting factor deficiency ... Autoimmune Vasculitis (lupus ... - Nutritional deficiency ... Work Up: •
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... blood cells appear normal ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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