11 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
celiac disease, CF ... Medications - Heparin ... ) • Advanced Liver ... • Acute DIC - Septic ... Summary #table #comparison
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Causes #diagnosis #differential
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... . heparin contamination ... thrombin inhibitors, heparin ... • Reduced liver ... amyloidosis #Abnormal
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... Acquired: • Heparin ... PT/NORMAL PTT: ... PT/ABNORMAL PTT
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... #Lesions #Hepatic ... CT #MRI #POCUS #radiology ... #differential # ... diagnosis #comparison
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... Arterial Phase, Portal ... #Lesions #Hepatic ... #differential # ... diagnosis #comparison
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT ... protein C and S Pathophysiology ... Fibrinogen: ↓ • PT ... DIC • Severe Liver ... thrombopoietin deficiency
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
- Differential ... GFR • Acute liver ... failure: Hepatic ... Manifestations #Differential ... beriberi #nutrition #pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Drugs: - Oral ... Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... Venous #Arterial #pathophysiology
Appearance of Liver Lesions on Magnetic Resonance Imaging (MRI) - T2, T1 precontrast, T1 portal venous,
Appearance of Liver ... #Lesions #Hepatic ... MagneticResonance #radiology ... #differential # ... diagnosis #comparison