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abscess bruising causes cell children classification gammopathy gap globulin hepatology hodgkins liver lymphoma management mds mgus myelodysplasia myelodysplastic paraproteinemias plasmacytoma
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Cryoglobulinemic, Hypo/normo-complementemic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... blood cells appear normal ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... products that define normal ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... light chain • Normal ... Gap #ProteinGap #differential ... #diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
- Fanconi anaemia ... Platelet count normal ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
endocarditis) - Portal ... liver #abscess #pediatrics ... #children #peds ... #differential # ... diagnosis #hepatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
mainly in the oral ... tissue composed of monoclonal ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Hematology
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