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hematology algorithm hypertension management oncology antiphospholipid apml cardiomyopathy causes differentiation disorders erythematosus hypercoagulable hypertensive lupus monoclonal obstetrics paraproteinemias peripartum pregnancy
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... fever, myalgias, HoTN ... initiation • Differential ... 500 mg QD until normal
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm Primary (Essential) (95%) - Onset between age
Mislabelled - Repeatedly normal ... taken at home, work ... excess (Cushing syndrome ... Primary #Secondary #HTN ... #Cardiology #Differential
Hypertensive Disorders of Pregnancy Chronic Hypertension: • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg •
patients • HELLP: Syndrome ... meds • New onset ... so have high clinical ... #obstetrics #cardiology ... #differential #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
thrombosis+Pulm HTN ... Cryoglobulinemic, Hypo/normo-complementemic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Clinical Features ... flares • CRP normal ... #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... - 1 or more clinical ... #Algorithm #diagnosis ... #hematology
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... predisposition (TTN ... Clinical • Under-recognized ... sx overlap with normal ... #management #cardiology
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