16 results
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #Body #Bodies #Pathology ... #Hematology #Smear ... #Clinical #Microscopy
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Sickled red cells ... : Sickle cell disease ... #Analysis #hematology ... interpretation #clinical
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemoglobin Defects: Sickle ... cell anemia, Thalassemias ... Peripheral Blood Smear ... ↑ abnormal RBCs ... Differential #Diagnosis #hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Blood #Smear # ... Rouleaux #Formation #Hematology
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
times the size of normal ... neutrophils #BoneMarrow #Smear ... #Hematology #Pathology ... #Clinical
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... fatigue, bone pain, abnormal ... peripheral blood smear ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... syndrome (MDS) (normal ... megakaryocytes and a normal ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management