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diagnosis management mds algorithm aplastic blood causes cell classification differential electrophoresis elevatedmcv formation hodgkins indications lymphoma macrocytic macrocytosis microscopy myelodysplasia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm Normal ... RBCs in Rouleaux ... Dysplastic • Myelodysplastic ... WBCs - Normal ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... marrow) -dys- (abnormal ... cytopenias (usually anemia ... Management #treatment #hematology ... #oncology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... formation” wherein normal ... dilution with normal ... #Clinical #Pathology ... #Formation #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... • Aplastic Anemia ... blood cells appear normal ... Syndromes #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... • Hypocellular myelodysplastic ... syndrome (MDS) (normal ... megakaryocytes and a normal ... #oncology #hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... fatigue, bone pain, abnormal ... bleeding) • Rouleaux ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... products that define normal ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology
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