17 results
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... #formation #IgM ... gammopathy #MGUS #Clinical ... #Pathology #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein ... normal blood tends ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... formation. ... #formation #Clinical ... #Smear #Hematology ... #Pathology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Blood Smear • ... Anemia RBCs in Rouleaux ... Formation • Multiple ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... features in most cases ... leukemia #APL #APML #Pathology ... #Hematology #Clinical
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
bleeding) • Rouleaux ... formations noted ... on peripheral blood ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... organ damage Clinical ... significant fibrin clot formation ... Treat primary cause ... treatment #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... cells appear normal ... Syndromes #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... deficiency • blood ... hydroxyapatite crystal formation ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology